GGCT antibody (C-Term)

Catalog No. ABIN2790049

The Rabbit Polyclonal anti-GGCT antibody is suitable to detect GGCT in samples from Human, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for GGCT antibody (C-Term) (ABIN2790049)

Target: GGCT (gamma-Glutamylcyclotransferase (GGCT))

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGCT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GGCT Antibody

Binding Specificity: C-Term

Sequence: ESAPPSPQYK KIICMGAKEN GLPLEYQEKL KAIEPNDYTG KVSEEIEDII

Predicted Reactivity: Cow: 92%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against GGCT. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 188 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GGCT

Target: GGCT (gamma-Glutamylcyclotransferase (GGCT))

Alternative Name: GGCT

Background: The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: C7orf24, CRF21, FLJ11717, GCTG, Ggc, MGC3077, GGC
Protein Interaction Partner: HECW2, UBC, APP,
Protein Size: 188

Molecular Weight: 21 kDa

Gene ID: 79017

NCBI Accession: NM_024051, NP_076956

UniProt: O75223