PDE6G antibody (N-Term)

Catalog No. ABIN2790053

This Rabbit Polyclonal antibody specifically detects PDE6G in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for PDE6G antibody (N-Term) (ABIN2790053)

Target: PDE6G (phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6G antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE6G Antibody

Binding Specificity: N-Term

Sequence: GPVTPRKGPP KFKQRQTRQF KSKPPKKGVQ GFGDDIPGME GLGTDITVIC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PDE6G. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 87 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE6G

Target: PDE6G (phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G))

Alternative Name: PDE6G

Background: This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants.
Alias Symbols: DKFZp686C0587, MGC125749, PDEG
Protein Interaction Partner: L3MBTL3, BHLHE40, FNBP1, PDE6G, TRIP10, DNM2, MAPK3, SRC, GNAO1, ADRBK1, GRB2,
Protein Size: 87

Molecular Weight: 10 kDa

Gene ID: 5148

NCBI Accession: NM_002602, NP_002593

UniProt: P18545

Pathways: EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction