SNX6 antibody (Middle Region)

Catalog No. ABIN2790092

This Rabbit Polyclonal antibody specifically detects SNX6 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Rabbit and Zebrafish (Danio rerio).

Quick Overview for SNX6 antibody (Middle Region) (ABIN2790092)

Target: SNX6 (Sorting Nexin 6 (SNX6))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SNX6 Antibody

Binding Specificity: Middle Region

Sequence: DGVIVSGVKD VDDFFEHERT FLLEYHNRVK DASAKSDRMT RSHKSAADDY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against SNX6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SNX6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 418 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SNX6

Target: SNX6 (Sorting Nexin 6 (SNX6))

Alternative Name: SNX6

Background: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms.
Alias Symbols: MGC3157, MSTP010, TFAF2
Protein Interaction Partner: UBC, FAM129B, VPS35, VPS29, RTF1, ATG7, TSNAX, TSN, STAT1, SNX2, SHMT2, SHMT1, PAWR, H3F3A, GTF2A1, ATP6V1C1, APEH, ANP32E, CSNK2A2, SNX1, BRCA1, PHLPP1, COIL, GIT1, ELAVL1, NDEL1, DISC1, TNIK, CALM1, TPT1, SNX6, SNX4, BMPR1B, ACVR2B, ACVRL1, LEPR, TGFBR2
Protein Size: 418

Molecular Weight: 48 kDa

Gene ID: 58533

NCBI Accession: NM_152233, NP_689419

UniProt: Q9UNH7

Pathways: EGFR Signaling Pathway