BLOC1S3 antibody (N-Term)

Catalog No. ABIN2790099

The Rabbit Polyclonal anti-BLOC1S3 antibody (ABIN2790099) specifically detects BLOC1S3 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Sheep and Zebrafish (Danio rerio) samples.

Quick Overview for BLOC1S3 antibody (N-Term) (ABIN2790099)

Target: BLOC1S3 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLOC1S3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BLOC1S3 Antibody

Binding Specificity: N-Term

Sequence: RGRPTGLRVA GEAAETDSEP EPEPEPTAAP RDLPPLVVQR ESAEEAWGTE

Predicted Reactivity: Cow: 93%, Dog: 86%, Goat: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 79%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against BLOC1S3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 202 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BLOC1S3

Target: BLOC1S3 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))

Alternative Name: BLOC1S3

Background: This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism.
Alias Symbols: BLOS3, FLJ26641, FLJ26676, HPS8, RP
Protein Interaction Partner: BLOC1S3, BLOC1S2, BLOC1S1, DTNBP1, BLOC1S5, BLOC1S6, SNAPIN,
Protein Size: 202

Molecular Weight: 21 kDa

Gene ID: 388552

NCBI Accession: NM_212550, NP_997715

UniProt: Q6QNY0