BLOC1S3 antibody (N-Term)

Catalog No. ABIN2790099

This anti-BLOC1S3 antibody is a Rabbit Polyclonal antibody detecting BLOC1S3 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Sheep and Zebrafish (Danio rerio).

Quick Overview for BLOC1S3 antibody (N-Term) (ABIN2790099)

Target: BLOC1S3 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLOC1S3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BLOC1S3 Antibody

Binding Specificity: N-Term

Sequence: RGRPTGLRVA GEAAETDSEP EPEPEPTAAP RDLPPLVVQR ESAEEAWGTE

Predicted Reactivity: Cow: 93%, Dog: 86%, Goat: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 79%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against BLOC1S3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 202 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BLOC1S3

Target: BLOC1S3 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))

Alternative Name: BLOC1S3

Background: This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism.
Alias Symbols: BLOS3, FLJ26641, FLJ26676, HPS8, RP
Protein Interaction Partner: BLOC1S3, BLOC1S2, BLOC1S1, DTNBP1, BLOC1S5, BLOC1S6, SNAPIN,
Protein Size: 202

Molecular Weight: 21 kDa

Gene ID: 388552

NCBI Accession: NM_212550, NP_997715

UniProt: Q6QNY0