HCRTR1 antibody (N-Term)

Catalog No. ABIN2790108

This Rabbit Polyclonal antibody specifically detects HCRTR1 in WB. It exhibits reactivity toward Human, Rat, Rabbit, Dog, Cow and Guinea Pig.

Quick Overview for HCRTR1 antibody (N-Term) (ABIN2790108)

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Reactivity: Human, Rat, Rabbit, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCRTR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HCRTR1 Antibody

Binding Specificity: N-Term

Sequence: ATPGAQMGVP PGSREPSPVP PDYEDEFLRY LWRDYLYPKQ YEWVLIAAYV

Predicted Reactivity: Cow: 85%, Dog: 91%, Guinea Pig: 83%, Human: 100%, Rabbit: 79%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HCRTR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HCRTR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 425 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HCRTR1

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Alternative Name: HCRTR1

Background: The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.
Alias Symbols: OX1R
Protein Interaction Partner: ARRB2, ARRB1, HCRT, CNR1,
Protein Size: 425

Molecular Weight: 47 kDa

Gene ID: 3061

NCBI Accession: NM_001525, NP_001516

UniProt: O43613

Pathways: Feeding Behaviour