SUCLG1 antibody (N-Term)

Catalog No. ABIN2790137

Product Details anti-SUCLG1 Antibody

Target: SUCLG1 (Succinate-CoA Ligase, alpha Subunit (SUCLG1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUCLG1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GQTHLGLPVF NTVKEAKEQT GATASVIYVP PPFAAAAINE AIEAEIPLVV

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 92%

Characteristics: This is a rabbit polyclonal antibody against SUCLG1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 346 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SUCLG1

Target: SUCLG1 (Succinate-CoA Ligase, alpha Subunit (SUCLG1))

Alternative Name: SUCLG1 (SUCLG1 Products)

Background: This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion.
Alias Symbols: FLJ21114, FLJ43513, GALPHA, SUCLA1, MTDPS9
Protein Interaction Partner: SUMO2, ECT2, S100A16, SEPT11, RIF1, SEPT9, SELENBP1, SUCLA2, SUCLG2, SDHA, OXCT1, CHMP1B, UBC, MYC,
Protein Size: 346

Molecular Weight: 33 kDa

Gene ID: 8802

NCBI Accession: NM_003849, NP_003840

UniProt: P53597