Tpp2 antibody (N-Term)

Catalog No. ABIN2790237

The Rabbit Polyclonal anti-Tpp2 antibody has been validated for WB. It is suitable to detect Tpp2 in samples from Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog and Horse.

Quick Overview for Tpp2 antibody (N-Term) (ABIN2790237)

Target: Tpp2 (Tripeptidyl Peptidase II (Tpp2))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tpp2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Tpp2 Antibody

Binding Specificity: N-Term

Sequence: GAPGMQVTTD GKPKIVDIID TTGSGDVNTA TEVEPKDGEI VGLSGRVLKI

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TPP2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TPP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1249 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Tpp2

Target: Tpp2 (Tripeptidyl Peptidase II (Tpp2))

Alternative Name: TPP2

Background: This gene encodes a mammalian peptidase that, at neutral pH , removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase, the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class.
Alias Symbols: FLJ40359
Protein Interaction Partner: PPP1R16A, POLB, EHHADH, SUMO2, UBC, TRIM47, PLOD2, PPP1R12A, UBD, CDK2, SIRT7,
Protein Size: 1249

Molecular Weight: 138 kDa

Gene ID: 7174

NCBI Accession: NM_003291, NP_003282

UniProt: P29144