CNKSR2 antibody (C-Term)

Catalog No. ABIN2790244

Product Details anti-CNKSR2 Antibody

Target: CNKSR2 (Connector Enhancer of Kinase Suppressor of Ras 2 (CNKSR2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNKSR2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EEEEEEGEAA GENIGEKSES REEKLGDSLQ DLYRALEQAS LSPLGEHRIS

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CNKSR2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CNKSR2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1034 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNKSR2

Target: CNKSR2 (Connector Enhancer of Kinase Suppressor of Ras 2 (CNKSR2))

Alternative Name: CNKSR2 (CNKSR2 Products)

Synonyms: CNK2 antibody, KSR2 antibody, MAGUIN antibody, C030004A01 antibody, Cnk2 antibody, Ksr2 antibody, mKIAA0902 antibody, connector enhancer of kinase suppressor of Ras 2 antibody, CNKSR2 antibody, Cnksr2 antibody

Background: This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CNK2, KIAA0902, KSR2, MAGUIN
Protein Interaction Partner: TNIK, TNFAIP3, SHANK3, LRRC7, DLG2, INADL, DLG4, RGS3, SNTA1, DLG1, TJP1, DLG3, RALA, RLF, RAF1, MOB3B,
Protein Size: 1034

Molecular Weight: 114 kDa

Gene ID: 22866

NCBI Accession: NM_014927, NP_055742

UniProt: Q8WXI2