HGSNAT antibody (C-Term)

Catalog No. ABIN2790258

This Rabbit Polyclonal antibody specifically detects HGSNAT in WB. It exhibits reactivity toward Human, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit and Rat.

Quick Overview for HGSNAT antibody (C-Term) (ABIN2790258)

Target: HGSNAT (Heparan-alpha-Glucosaminide N-Acetyltransferase (HGSNAT))

Reactivity: Human, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HGSNAT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HGSNAT Antibody

Binding Specificity: C-Term

Sequence: VKGLWTGTPF FYPGMNSILV YVGHEVFENY FPFQWKLKDN QSHKEHLTQN

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against HGSNAT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human HGSNAT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 635 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HGSNAT

Target: HGSNAT (Heparan-alpha-Glucosaminide N-Acetyltransferase (HGSNAT))

Alternative Name: HGSNAT

Background: This gene encodes a lysosomal acetyltransferase, which is one of several enzymes involved in the lysosomal degradation of heparin sulfate. Mutations in this gene are associated with Sanfilippo syndrome C, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate.
Alias Symbols: DKFZp686G24175, FLJ22242, FLJ32731, HGNAT, MPS3C, TMEM76
Protein Size: 635

Molecular Weight: 2 kDa

Gene ID: 138050

NCBI Accession: NM_152419, NP_689632

UniProt: Q68CP4

Pathways: Glycosaminoglycan Metabolic Process