ANKS1B antibody (C-Term)

Catalog No. ABIN2790321

The Rabbit Polyclonal anti-ANKS1B antibody has been validated for WB. It is suitable to detect ANKS1B in samples from Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for ANKS1B antibody (C-Term) (ABIN2790321)

Target: ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKS1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ANKS1B Antibody

Binding Specificity: C-Term

Sequence: ACAKMRANCQ KSTEQMKKVP TIILSVSYKG VKFIDATNKN IIAEHEIRNI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ANKS1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ANKS1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 357 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ANKS1B

Target: ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))

Alternative Name: ANKS1B

Background: This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1,19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene.
Alias Symbols: AIDA, AIDA-1, ANKS2, EB-1, EB1, MGC26087, cajalin-2
Protein Interaction Partner: UBC, ERBB4, ERBB2, EGFR, APP, LRP1, LRP2, HTR2A, COIL,
Protein Size: 357

Molecular Weight: 40 kDa

Gene ID: 56899

NCBI Accession: NM_001204066, NP_001190995

UniProt: F8VZR9