ANKS1B antibody (C-Term)

Catalog No. ABIN2790322

This anti-ANKS1B antibody is a Rabbit Polyclonal antibody detecting ANKS1B in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig and Zebrafish (Danio rerio).

Quick Overview for ANKS1B antibody (C-Term) (ABIN2790322)

Target: ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKS1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ANKS1B Antibody

Binding Specificity: C-Term

Sequence: PSKPIPKPRV SIRKSVQIDP SEQKTLANLP WIVEPGQEAK RGINTKYETT

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ANKS1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ANKS1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 510 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ANKS1B

Target: ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))

Alternative Name: ANKS1B

Background: This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1,19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene.
Alias Symbols: AIDA, AIDA-1, ANKS2, EB-1, EB1, MGC26087, cajalin-2
Protein Interaction Partner: UBC, ERBB4, ERBB2, EGFR, APP, LRP1, LRP2, HTR2A, COIL,
Protein Size: 510

Molecular Weight: 58 kDa

Gene ID: 56899

NCBI Accession: NM_181670, NP_858056

UniProt: Q7Z6G8