ACER2 antibody (Middle Region)

Catalog No. ABIN2790349

This anti-ACER2 antibody is a Rabbit Polyclonal antibody detecting ACER2 in WB. Suitable for Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog and Zebrafish (Danio rerio).

Quick Overview for ACER2 antibody (Middle Region) (ABIN2790349)

Target: ACER2 (Alkaline Ceramidase 2 (ACER2))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACER2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACER2 Antibody

Binding Specificity: Middle Region

Sequence: DELAVLWVLM CALAMWFPRR YLPKIFRNDR GRFKVVVSVL SAVTTCLAFV

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against ACER2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ACER2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 275 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACER2

Target: ACER2 (Alkaline Ceramidase 2 (ACER2))

Alternative Name: ACER2

Background: The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine.
Alias Symbols: ASAH3L, FLJ41587
Protein Size: 275

Molecular Weight: 31 kDa

Gene ID: 340485

NCBI Accession: NM_001010887, NP_001010887

UniProt: Q5QJU3

Pathways: Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process