GPLD1 antibody (N-Term)

Catalog No. ABIN2790409

Product Details anti-GPLD1 Antibody

Target: GPLD1 (Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPLD1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GKFHDVSEST HWTPFLNASV HYIRENYPLP WEKDTEKLVA FLFGITSHMA

Predicted Reactivity: Cow: 85%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GPLD1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GPLD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 840 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPLD1

Target: GPLD1 (Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1))

Alternative Name: GPLD1 (GPLD1 Products)

Background: Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane.
Alias Symbols: GPIPLD, GPIPLDM, MGC22590, PIGPLD, PIGPLD1
Protein Interaction Partner: APOA1, GM2A, ALPP, CD55, APOA4,
Protein Size: 840

Molecular Weight: 90 kDa

Gene ID: 2822

NCBI Accession: NM_001503, NP_001494

UniProt: P80108

Pathways: Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process