SNTG2 antibody (C-Term)

Catalog No. ABIN2790447

This Rabbit Polyclonal antibody specifically detects SNTG2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for SNTG2 antibody (C-Term) (ABIN2790447)

Target: SNTG2 (Syntrophin, gamma 2 (SNTG2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNTG2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SNTG2 Antibody

Binding Specificity: C-Term

Sequence: NVLWRFKFSQ LKGSSDDGKT RVKLLFQNLD TKQIETKELE FQDLRAVLHC

Predicted Reactivity: Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SNTG2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SNTG2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SNTG2

Target: SNTG2 (Syntrophin, gamma 2 (SNTG2))

Alternative Name: SNTG2

Background: This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.
Alias Symbols: G2SYN, SYN5
Protein Interaction Partner: MPP3, BAI1, DTNB, DTNA, SCN5A, DMD,
Protein Size: 539

Molecular Weight: 59 kDa

Gene ID: 54221

NCBI Accession: NM_018968, NP_061841

UniProt: Q9NY99