SNTG2 antibody (C-Term)

Catalog No. ABIN2790447

Product Details anti-SNTG2 Antibody

Target: SNTG2 (Syntrophin, gamma 2 (SNTG2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNTG2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NVLWRFKFSQ LKGSSDDGKT RVKLLFQNLD TKQIETKELE FQDLRAVLHC

Predicted Reactivity: Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SNTG2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SNTG2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SNTG2

Target: SNTG2 (Syntrophin, gamma 2 (SNTG2))

Alternative Name: SNTG2 (SNTG2 Products)

Background: This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.
Alias Symbols: G2SYN, SYN5
Protein Interaction Partner: MPP3, BAI1, DTNB, DTNA, SCN5A, DMD,
Protein Size: 539

Molecular Weight: 59 kDa

Gene ID: 54221

NCBI Accession: NM_018968, NP_061841

UniProt: Q9NY99