TMBIM4 antibody (Middle Region)

Catalog No. ABIN2790594

The Rabbit Polyclonal anti-TMBIM4 antibody has been validated for WB. It is suitable to detect TMBIM4 in samples from Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for TMBIM4 antibody (Middle Region) (ABIN2790594)

Target: TMBIM4 (Transmembrane BAX Inhibitor Motif Containing 4 (TMBIM4))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMBIM4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMBIM4 Antibody

Binding Specificity: Middle Region

Sequence: LTVAVVVTFY DVYIILQAFI LTTTVFFGLT VYTLQSKKDF SKFGAGLFAL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TMBIM4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human TMBIM4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 258 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TMBIM4

Target: TMBIM4 (Transmembrane BAX Inhibitor Motif Containing 4 (TMBIM4))

Alternative Name: TMBIM4

Background: TMBIM4 is an anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. It can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release.
Alias Symbols: CGI-119, GAAP, S1R, ZPRO, LFG4
Protein Interaction Partner: VKORC1, CCDC47, SLC27A4, RPN2, PRPSAP1, PPIB, MTX1, DFFA, DDOST, COX4I1,
Protein Size: 258

Molecular Weight: 28 kDa

Gene ID: 51643

NCBI Accession: NM_016056, NP_057140

UniProt: Q9HC24