SERF1A antibody (N-Term)

Catalog No. ABIN2790696

This Rabbit Polyclonal antibody specifically detects SERF1A in WB. It exhibits reactivity toward Human, Guinea Pig, Mouse, Rat, Cow and Rabbit.

Quick Overview for SERF1A antibody (N-Term) (ABIN2790696)

Target: SERF1A (Small EDRK-Rich Factor 1A (Telomeric) (SERF1A))

Reactivity: Human, Guinea Pig, Mouse, Rat, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERF1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SERF1A Antibody

Binding Specificity: N-Term

Sequence: KNMKKTQEIS KGKRKEDSLT ASQRKQRDSE IMQEKQKAAN EKKSMQTREK

Predicted Reactivity: Cow: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SERF1A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SERF1A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 62 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SERF1A

Target: SERF1A (Small EDRK-Rich Factor 1A (Telomeric) (SERF1A))

Alternative Name: SERF1A

Background: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The duplication region includes both a telomeric and a centromeric copy of this gene. Deletions of this gene, the telomeric copy, often accompany deletions of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients, and so it is thought that this gene may be a modifier of the SMA phenotype. The function of this protein is not known, however, it bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product.
Alias Symbols: 4F5, FAM2A, H4F5, SERF1, SERF1B, SMAM1
Protein Interaction Partner: UBC, APP, PIK3R3,
Protein Size: 62

Molecular Weight: 6 kDa

Gene ID: 8293

NCBI Accession: NM_022968, NP_075257

UniProt: O75920