ALG10B antibody (N-Term)

Catalog No. ABIN2790718

The Rabbit Polyclonal anti-ALG10B antibody is suitable to detect ALG10B in samples from Human, Dog, Horse, Rat, Guinea Pig, Mouse and Rabbit. It has been validated for WB.

Quick Overview for ALG10B antibody (N-Term) (ABIN2790718)

Target: ALG10B (Asparagine-Linked Glycosylation 10, alpha-1,2-Glucosyltransferase Homolog B (ALG10B))

Reactivity: Human, Dog, Horse, Rat, Guinea Pig, Mouse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALG10B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALG10B Antibody

Binding Specificity: N-Term

Sequence: SVGNFYLLYL LFHKVQPRNK AASSIQRVLS TLTLAVFPTL YFFNFLYYTE

Predicted Reactivity: Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ALG10B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ALG10B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 473 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALG10B

Target: ALG10B (Asparagine-Linked Glycosylation 10, alpha-1,2-Glucosyltransferase Homolog B (ALG10B))

Alternative Name: ALG10B

Background: ALG10B is a putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. ALG10B transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2.
Alias Symbols: ALG10, KCR1
Protein Interaction Partner: UBC, KCNH2,
Protein Size: 473

Molecular Weight: 55 kDa

Gene ID: 144245

NCBI Accession: NM_001013620, NP_001013642

UniProt: Q5I7T1