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CCDC99 antibody (C-Term)

This anti-CCDC99 antibody is a Rabbit Polyclonal antibody detecting CCDC99 in WB. Suitable for Human, Rat, Cow, Dog, Horse, Pig and Rabbit.
Catalog No. ABIN2790740

Quick Overview for CCDC99 antibody (C-Term) (ABIN2790740)

Target

See all CCDC99 Antibodies
CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))

Reactivity

Human, Rat, Cow, Dog, Horse, Pig, Rabbit

Host

  • 38
  • 3
Rabbit

Clonality

  • 39
  • 2
Polyclonal

Conjugate

  • 16
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CCDC99 antibody is un-conjugated

Application

  • 17
  • 14
  • 13
  • 13
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 15
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequence

    PRLAAESKLQ TEVKEGKETS SKLEKETCKK LHPILYVSSK STPETQCPQQ

    Predicted Reactivity

    Cow: 79%, Dog: 93%, Horse: 92%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 79%

    Characteristics

    This is a rabbit polyclonal antibody against CCDC99. It was validated on Western Blot.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human CCDC99
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 605 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))

    Alternative Name

    CCDC99

    Background

    CCDC99 is required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. CCDC99 is also required for correct spindle orientation. It does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
    Alias Symbols: FLJ20364, FLJ40690, CCDC99
    Protein Interaction Partner: RTP5, PPP1R18, DYX1C1, SPDL1, USP15, TRAF4, CA8, NEK9, SIRT1, HMGCS1, DHX40, YLPM1, SF3B3, ITSN1, UBC, KIAA1377, GPS2,
    Protein Size: 605

    Molecular Weight

    67 kDa

    Gene ID

    54908

    NCBI Accession

    NM_017785, NP_060255

    UniProt

    Q96EA4
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