FBXO17 antibody (N-Term)

Catalog No. ABIN2790788

The Rabbit Polyclonal anti-FBXO17 antibody is suitable to detect FBXO17 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig and Rabbit. It has been validated for WB.

Quick Overview for FBXO17 antibody (N-Term) (ABIN2790788)

Target: FBXO17 (F-Box Protein 17 (FBXO17))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO17 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXO17 Antibody

Binding Specificity: N-Term

Sequence: VQVLSHVPPR SLVTRCRPVC RAWRDIVDGP TVWLLQLARD RSAEGRALYA

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO17. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXO17

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 287 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO17

Target: FBXO17 (F-Box Protein 17 (FBXO17))

Alternative Name: FBXO17

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing of this gene results in 2 transcript variants encoding different isoforms
Alias Symbols: FBG4, FBX26, FBXO26, FLJ11798, FLJ25205, FLJ58300, Fbx17, MGC9379
Protein Interaction Partner: SKP1, HSP90AA1, COPS3, COPS4, COPS5, COPS6, CUL1, CUL5, RBX1, UBC,
Protein Size: 287

Molecular Weight: 32 kDa

Gene ID: 115290

NCBI Accession: NM_148169, NP_680474