IST1 antibody (N-Term)

Catalog No. ABIN2790798

This Rabbit Polyclonal antibody specifically detects IST1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for IST1 antibody (N-Term) (ABIN2790798)

Target: IST1 (Increased Sodium Tolerance 1 Homolog (IST1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IST1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IST1 Antibody

Binding Specificity: N-Term

Sequence: INRLKLLEKK KTELAQKARK EIADYLAAGK DERARIRVEH IIREDYLVEA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against IST1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human IST1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 360 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IST1

Target: IST1 (Increased Sodium Tolerance 1 Homolog (IST1))

Alternative Name: IST1

Background: IST1 is proposed to be involved in specific functions of the ESCRT machinery. It is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvment in the MVB pathway is not established. IST1 is involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.
Alias Symbols: IST1, MGC117220
Protein Interaction Partner: APEH, UBQLN1, CAPN7, UBC, BTF3L4, TIMM13, VCAM1, ITGA4, FN1, ERGIC1, MAT1A, HSPA5, ATP6V1B1, ATXN1, SPAST, FZR1, ANAPC2, CDC20, CHMP1B,
Protein Size: 360

Molecular Weight: 40 kDa

Gene ID: 9798

NCBI Accession: NM_014761, NP_055576

Pathways: Regulation of Cell Size