NUBPL antibody (N-Term)

Catalog No. ABIN2790828

Product Details anti-NUBPL Antibody

Target: NUBPL (Nucleotide Binding Protein-Like (NUBPL))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUBPL antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MGIWQRLLLF GGVSLRAGGG ATAPLGGSRA MVCGRQLSGA GSETLKQRRT

Predicted Reactivity: Cow: 92%, Dog: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 83%, Rabbit: 85%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against NUBPL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NUBPL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 319 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NUBPL

Target: NUBPL (Nucleotide Binding Protein-Like (NUBPL))

Alternative Name: NUBPL (NUBPL Products)

Background: This gene encodes a member of the Mrp/NBP35 ATP-binding proteins family. The encoded protein is required for the assembly of the respiratory chain NADH dehydrogenase (complex I), an oligomeric enzymatic complex located in the inner mitochondrial membrane. The respiratory complex I consists of 45 subunits and 8 iron-sulfur (Fe/S) clusters. This protein is an Fe/S protein that plays a critical role in the assembly of respiratory complex I, likely by transferring Fe/S into the Fe/S-containing complex I subunits. Mutations in this gene cause mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Alias Symbols: C14orf127, FLJ12660, IND1
Protein Interaction Partner: MTUS2, RNF2,
Protein Size: 319

Molecular Weight: 34 kDa

Gene ID: 80224

NCBI Accession: NM_025152, NP_079428