SYT14 antibody (Middle Region)

Catalog No. ABIN2790867

This anti-SYT14 antibody is a Rabbit Polyclonal antibody detecting SYT14 in WB. Suitable for Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat and Zebrafish (Danio rerio).

Quick Overview for SYT14 antibody (Middle Region) (ABIN2790867)

Target: SYT14 (Synaptotagmin XIV (SYT14))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYT14 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SYT14 Antibody

Binding Specificity: Middle Region

Sequence: HCSNSPRCSY NKCPSEGSTG HEIESFHNKG YEEDVPSDST AVLSPEDMSA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SYT14. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SYT14

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 555 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SYT14

Target: SYT14 (Synaptotagmin XIV (SYT14))

Alternative Name: SYT14

Background: This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptotagmin. Mutations in this gene are a cause of autosomal recessive spinocerebellar ataxia-11 (SCAR11), and a t(1,3) translocation of this gene has been associated with neurodevelopmental abnormalities. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4.
Alias Symbols: SCAR11, sytXIV
Protein Interaction Partner: SYT16, SYT14,
Protein Size: 555

Molecular Weight: 62 kDa

Gene ID: 255928

NCBI Accession: NM_153262, NP_694994

UniProt: Q8NB59