YOD1 antibody (C-Term)

Catalog No. ABIN2790890

The Rabbit Polyclonal anti-YOD1 antibody (ABIN2790890) specifically detects YOD1 in WB. The antibody is reactive with Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) and Cow samples.

Quick Overview for YOD1 antibody (C-Term) (ABIN2790890)

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YOD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-YOD1 Antibody

Binding Specificity: C-Term

Sequence: ELADEARRRR QFTDVNRFTL RCMVCQKGLT GQAEAREHAK ETGHTNFGEV

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against YOD1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human YOD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 348 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for YOD1

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Alternative Name: YOD1

Background: Deubiquitinating enzymes are proteases that specifically cleave ubiquitin linkages, negating the action of ubiquitin ligases. DUBA8 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.
Alias Symbols: DUBA8, OTUD2, PRO0907
Protein Interaction Partner: NPLOC4, VCP, UFD1L, RIPK1, UBE3A, UBC, NEDD4, SYVN1, TRA, AMFR, TRIM63, TRIM54, USP21, USP15, TRIM55, UBE2J1, ELAVL1, DERL1, FAF2, THOC3, BLOC1S5, YOD1,
Protein Size: 348

Molecular Weight: 38 kDa

Gene ID: 55432

NCBI Accession: NM_018566, NP_061036

UniProt: Q5VVQ6

Pathways: ER-Nucleus Signaling