The Rabbit Polyclonal anti-ATP6V0E2 antibody is suitable to detect ATP6V0E2 in samples from Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat and Zebrafish (Danio rerio). It has been validated for WB.
Multisubunit vacuolar-type proton pumps, or H(+)-ATPases, acidify various intracellular compartments, such as vacuoles, clathrin-coated and synaptic vesicles, endosomes, lysosomes, and chromaffin granules. H(+)-ATPases are also found in plasma membranes of specialized cells, where they play roles in urinary acidification, bone resorption, and sperm maturation. Multiple subunits form H(+)-ATPases, with proteins of the V1 class hydrolyzing ATP for energy to transport H+, and proteins of the V0 class forming an integral membrane domain through which H+ is transported. ATP6V0E2 encodes an isoform of the H(+)-ATPase V0 e subunit, an essential proton pump component. Alias Symbols: ATP6V0E2L, C7orf32 Protein Interaction Partner: RBPMS, Protein Size: 187