FBXO44 antibody (Middle Region)
Quick Overview for FBXO44 antibody (Middle Region) (ABIN2791019)
Target
See all FBXO44 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- LDVNGGDEWK VEDLSRDQRK EFPNDQVKKY FVTSYYTCLK SQVVDLKAEG
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Predicted Reactivity
- Cow: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%
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Characteristics
- This is a rabbit polyclonal antibody against FBXO44. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human FBXO44
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 255 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FBXO44 (F-Box Protein 44 (FBXO44))
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Alternative Name
- FBXO44
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Background
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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Four alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene.
Alias Symbols: FBG3, FBX30, FBX6A, Fbx44, Fbxo6a
Protein Interaction Partner: C17orf59, SERTAD3, SKP1, UBC, BRCA1, BARD1, COPS5, COPS6, RBX1, CUL1, KIAA0368,
Protein Size: 255 -
Molecular Weight
- 28 kDa
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Gene ID
- 93611
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NCBI Accession
- NM_033182, NP_149438
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UniProt
- Q9H4M3
Target
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