APOPT1 antibody (C-Term)

Catalog No. ABIN2791221

This anti-APOPT1 antibody is a Rabbit Polyclonal antibody detecting APOPT1 in WB. Suitable for Human, Cow and Horse.

Quick Overview for APOPT1 antibody (C-Term) (ABIN2791221)

Target: APOPT1 (Apoptogenic 1, Mitochondrial (APOPT1))

Reactivity: Human, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOPT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APOPT1 Antibody

Binding Specificity: C-Term

Sequence: KEFLSKNFQK HMYYNRDWYK RNFAITFFMG KVALERIWNK LKQKQKKRSN

Predicted Reactivity: Cow: 82%, Horse: 82%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against APOPT1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human APOPT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 206 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for APOPT1

Target: APOPT1 (Apoptogenic 1, Mitochondrial (APOPT1))

Alternative Name: APOPT1

Background: APOPT1 plays a role in the regulation of apoptosis. It mediates mitochondria-induced cell death in vascular smooth muscle cells through the release of cytochrome c from mitochondria, followed by the activation of the caspase cascade.
Alias Symbols: APOP1, C14orf153
Protein Interaction Partner: BAG3, UBC,
Protein Size: 206

Molecular Weight: 20 kDa

Gene ID: 84334

NCBI Accession: NM_032374, NP_115750

UniProt: Q96IL0

Pathways: Positive Regulation of Endopeptidase Activity