MYL12B antibody (C-Term)

Catalog No. ABIN2791276

Product Details anti-MYL12B Antibody

Target: MYL12B (Myosin, Light Chain 12B, Regulatory (MYL12B))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Goat, Guinea Pig, Horse, Rabbit, Sheep, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYL12B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EKLNGTDPED VIRNAFACFD EEATGTIQED YLRELLTTMG DRFTDEEVDE

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against MYL12B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MYL12B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 172 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYL12B

Target: MYL12B (Myosin, Light Chain 12B, Regulatory (MYL12B))

Alternative Name: MYL12B (MYL12B Products)

Background: The activity of nonmuscle myosin II is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments.
Alias Symbols: MLC-B, MRLC2
Protein Interaction Partner: HAUS1, UBC, UBD, PAN2, ITGA4, DAPK1, LRRK2, MYLIP, CUL1, CDK2, FBXO25, ARRB1, SUMO2, YWHAQ, USP45, PNKD,
Protein Size: 172

Molecular Weight: 20 kDa

Gene ID: 103910

NCBI Accession: NM_033546, NP_291024

UniProt: O14950

Pathways: Feeding Behaviour