MYL12B antibody (C-Term)

Catalog No. ABIN2791276

This Rabbit Polyclonal antibody specifically detects MYL12B in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Goat, Guinea Pig, Horse, Rabbit, Sheep, Dog and Zebrafish (Danio rerio).

Quick Overview for MYL12B antibody (C-Term) (ABIN2791276)

Target: MYL12B (Myosin, Light Chain 12B, Regulatory (MYL12B))

Reactivity: Human, Mouse, Rat, Cow, Goat, Guinea Pig, Horse, Rabbit, Sheep, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYL12B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MYL12B Antibody

Binding Specificity: C-Term

Sequence: EKLNGTDPED VIRNAFACFD EEATGTIQED YLRELLTTMG DRFTDEEVDE

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against MYL12B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MYL12B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 172 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYL12B

Target: MYL12B (Myosin, Light Chain 12B, Regulatory (MYL12B))

Alternative Name: MYL12B

Background: The activity of nonmuscle myosin II is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments.
Alias Symbols: MLC-B, MRLC2
Protein Interaction Partner: HAUS1, UBC, UBD, PAN2, ITGA4, DAPK1, LRRK2, MYLIP, CUL1, CDK2, FBXO25, ARRB1, SUMO2, YWHAQ, USP45, PNKD,
Protein Size: 172

Molecular Weight: 20 kDa

Gene ID: 103910

NCBI Accession: NM_033546, NP_291024

UniProt: O14950

Pathways: Feeding Behaviour