C1orf86 antibody (C-Term)

Catalog No. ABIN2791345

The Rabbit Polyclonal anti-C1orf86 antibody has been validated for WB. It is suitable to detect C1orf86 in samples from Human.

Quick Overview for C1orf86 antibody (C-Term) (ABIN2791345)

Target: C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1orf86 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C1orf86 Antibody

Binding Specificity: C-Term

Sequence: ARSLPQRPAP DPCRAPRVEQ QPSVEGAAAL RSCPMCQKEF APRLTQLDVD

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against C1orf86. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human C1orf86

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 180 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C1orf86

Target: C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))

Alternative Name: C1orf86

Background: C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.
Alias Symbols: FP7162
Protein Interaction Partner: FANCL, FANCA, UBC, FANCC, APITD1, C19orf40, C17orf70, FANCM, REV1, FANCG, FANCF, FANCB, FANCE, ELAVL1,
Protein Size: 180

Molecular Weight: 19 kDa

Gene ID: 199990

NCBI Accession: NM_182533, NP_872339

UniProt: Q6NZ36