HENMT1 antibody (N-Term)

Catalog No. ABIN2791578

The Rabbit Polyclonal anti-HENMT1 antibody is suitable to detect HENMT1 in samples from Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for HENMT1 antibody (N-Term) (ABIN2791578)

Target: HENMT1 (HEN1 Methyltransferase Homolog 1 (HENMT1))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HENMT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HENMT1 Antibody

Binding Specificity: N-Term

Sequence: RETAIQFKPP LYRQRYQFVK NLVDQHEPKK VADLGCGDTS LLRLLKVNPC

Predicted Reactivity: Cow: 86%, Dog: 91%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against HENMT1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HENMT1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HENMT1

Target: HENMT1 (HEN1 Methyltransferase Homolog 1 (HENMT1))

Alternative Name: HENMT1

Background: HENMT1 is a methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.
Alias Symbols: C1orf59, HEN1
Protein Interaction Partner: TRAF2, UBC,
Protein Size: 393

Molecular Weight: 43 kDa

Gene ID: 113802

NCBI Accession: NM_144584, NP_653185

UniProt: Q5T8I9