IFIT1 antibody (Middle Region)

Catalog No. ABIN2791584

The Rabbit Polyclonal anti-IFIT1 antibody (ABIN2791584) specifically detects IFIT1 in WB. The antibody is reactive with Human, Cow, Dog, Horse, Pig and Rabbit samples.

Quick Overview for IFIT1 antibody (Middle Region) (ABIN2791584)

Target: IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))

Reactivity: Human, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFIT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IFIT1 Antibody

Binding Specificity: Middle Region

Sequence: PFRYRMECPE IDCEEGWALL K
CGGKNYERAK ACFEKVLEVD PENPESSA

Predicted Reactivity: Cow: 92%, Dog: 85%, Horse: 85%, Human: 100%, Pig: 92%, Rabbit: 92%

Characteristics: This is a rabbit polyclonal antibody against IFIT1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human IFIT1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IFIT1

Target: IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))

Alternative Name: IFIT1

Background: This gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely related genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Protein Interaction Partner: IFIT3, UBC, SUMO1, IFIT1B, DCD, TOE1, GRPEL1, MCCC2, MCCC1, PABPC1, IFIT5, IGF2BP1, PABPC4, SNRPF, SNRPE, SNRPD3, SNRPD2, SNRPD1, SNRPC, SNRPB2, SNRPB, SNRPA1, SNRPA, SNRNP70, S100A7, RPLP1, PCCB, PCCA, PC, YBX1, NCL, MOV10, ILF2, IFIT2, HSP90AB1, HSP90AA
Protein Size: 447

Molecular Weight: 49 kDa

Gene ID: 3434

NCBI Accession: NP_001257859

UniProt: D3DR31

Pathways: Hepatitis C