PSMD5 antibody (C-Term)

Catalog No. ABIN2791885

The Rabbit Polyclonal anti-PSMD5 antibody (ABIN2791885) specifically detects PSMD5 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for PSMD5 antibody (C-Term) (ABIN2791885)

Target: PSMD5 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 5 (PSMD5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PSMD5 Antibody

Binding Specificity: C-Term

Sequence: FEMIESQDPT MIGVAVDTVG ILGSNVEGKQ VLQKTGTRFE RLLMRIGHQS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PSMD5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PSMD5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSMD5

Target: PSMD5 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 5 (PSMD5))

Alternative Name: PSMD5

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly.
Alias Symbols: S5B
Protein Interaction Partner: UBC, TFCP2, PSMC2, PSMC1, PPME1, GMPS, PNP, PARK2, RNF11, BAG3, FN1, MACF1, PSMD13, PSMD7, PSMD2, PSMD1, PSMB5, PSMB4, PSMB2, PSMB1, PSMA7, PSMA6, PSMA4, PSMA2, PSMA1, APP, PSMD4, COPS2, RAD23A, ELAVL1, PMS2, RPN7, RPN2, RPT1, RPT2,
Protein Size: 504

Molecular Weight: 55 kDa

Gene ID: 5711

NCBI Accession: NM_005047, NP_005038

UniProt: Q16401

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway