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DSCR3 antibody (Middle Region)
DSCR3
Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DSCR3 Antibody
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Target
See all DSCR3 Antibodies
DSCR3
(Down Syndrome Critical Region Gene 3 (DSCR3))
Binding Specificity
All epitopes for DSCR3 antibodies
Middle Region
Reactivity
Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit
Host
All hosts for DSCR3 antibodies
Rabbit
Clonality
All clonalities for DSCR3 antibodies
Polyclonal
Conjugate
All conjugates for DSCR3 antibodies
This DSCR3 antibody is un-conjugated
Application
All applications for DSCR3 antibodies
Western Blotting (WB)
Sequence
SAPQKGKFTP SPVDFTITPE TLQNVKERAL LPKFLLRGHL NSTNCVITQP
Predicted Reactivity
Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
Characteristics
This is a rabbit polyclonal antibody against DSCR3. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human DSCR3
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for DSCR3
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Target
DSCR3
(Down Syndrome Critical Region Gene 3 (DSCR3))
Alternative Name
DSCR3 (DSCR3 Products )
Background
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. Alias Symbols: DCRA, DSCRA Protein Size: 249
Molecular Weight
27 kDa
Gene ID
10311
NCBI Accession
XM_011529423 , XP_011527725
UniProt
A8MTY9
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