SERPINA1 antibody (C-Term)

Catalog No. ABIN2792095

This Rabbit Polyclonal antibody specifically detects SERPINA1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for SERPINA1 antibody (C-Term) (ABIN2792095)

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SERPINA1 Antibody

Binding Specificity: C-Term

Sequence: TEAAGAMFLE AIPMSIPPEV KFNKPFVFLM IEQNTKSPLF MGKVVNPTQK

Characteristics: This is a rabbit polyclonal antibody against SERPINA1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SERPINA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 418 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SERPINA1

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Alternative Name: SERPINA1

Background: Alpha-1-antitrypsin is a protease inhibitor, deficiency of which is associated with emphysema and liver disease. The protein is encoded by a gene (PI) located on the distal long arm of chromosome 14.
Alias Symbols: PI, A1A, AAT, PI1, A1AT, PRO2275, alpha1AT
Protein Interaction Partner: DERL1, DERL2, FN1, RCHY1, SSR1, SDC2, SMAD4, ECHS1, CANX, ATP5C1, GSDMB, VKORC1, ERLEC1, OS9, VCP, UBC, RAP2A, MIS12, DERL3, PRSS3, KLK5, MMP26, ADAMTS4, PRSS2, SERPINA1, PRSS1, MMP11, MMP7, PRTN3, KLK3, ELANE, CELA1, CTRB1, CTSG, LRP1, KLK13,
Protein Size: 418

Molecular Weight: 46 kDa

Gene ID: 5265

NCBI Accession: NM_000295, NP_000286

UniProt: P01009