Histone H3.3 antibody (N-Term)

Catalog No. ABIN2792109

This anti-Histone H3.3 antibody is a Rabbit Polyclonal antibody detecting Histone H3.3 in WB. Suitable for Human.

Quick Overview for Histone H3.3 antibody (N-Term) (ABIN2792109)

Target: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H3.3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Histone H3.3 Antibody

Binding Specificity: N-Term

Sequence: MARTKQTARK STGGKAPRKQ LATKVARKSA PATGGVKKPH RYRPGTVALR

Characteristics: This is a rabbit polyclonal antibody against H3F3A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HIST3H3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 136 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Histone H3.3

Target: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Alternative Name: H3F3A (H3F3A)

Background: Histone H3, along with histone H4, plays a central role in nucleosome formation.
Alias Symbols: H3t, H3.4, H3/g, H3FT, H3F3A
Protein Interaction Partner: RAD6, SETD7, WHSC1L1, PRDM2, WHSC1, KMT2A, PHF7, CBX5, TRIM28, ING2, UBC, K07C5.3, APLF, UHRF1, NEDD8, CUL4A, EZH2, ASF1B, ASF1A, MMS22L, IGSF8, TONSL, ICAM1, CD81, AURKA, MLLT1, TAF8, TAF3, TAF9B, PHF21A, ING4, PRAME, KAT6B, CBX6, PHF8, PHF2, ITGA4, TAF1
Protein Size: 136

Molecular Weight: 15 kDa

Gene ID: 8290

NCBI Accession: NM_002107, NP_002098

UniProt: Q16695