SFRP1 antibody (Middle Region)

Catalog No. ABIN2792235

This Rabbit Polyclonal antibody specifically detects SFRP1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse and Guinea Pigand has been mentioned in 1 publication.

Quick Overview for SFRP1 antibody (Middle Region) (ABIN2792235)

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SFRP1 Antibody

Binding Specificity: Middle Region

Sequence: HQLDNLSHHF LIMGRKVKSQ YLLTAIHKWD KKNKEFKNFM KKMKNHECPT

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SFRP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SFRP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 314 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SFRP1 antibody (ABIN2792235)

Qiu, Xu, Zhou, Shi, Ma, Li, Li: "Involvement of genetic instability in the downregulation of sFRP1 in Chinese patients with hepatocellular carcinoma." in: Anatomical record (Hoboken, N.J. : 2007), Vol. 293, Issue 12, pp. 2020-6, (2010) (PubMed).

Target Details for SFRP1

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Alternative Name: SFRP1

Background: Secreted frizzled-related protein 1 (SFRP1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 may be involved in de
Alias Symbols: FRP, FRP1, FrzA, FRP-1, SARP2
Protein Interaction Partner: KIAA1522, PPP1CC, PPP1CA, WNT4, FZD6, WNT1, WNT2,
Protein Size: 314

Molecular Weight: 35 kDa

Gene ID: 6422

NCBI Accession: NM_003012, NP_003003

UniProt: Q8N474

Pathways: WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation