SFRP1 antibody

Catalog No. ABIN7270179

The Rabbit Monoclonal anti-SFRP1 antibody (ABIN7270179) specifically detects SFRP1 in WB. The antibody is reactive with Human samples.

Quick Overview for SFRP1 antibody (ABIN7270179)

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SFRP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SFRP1 Antibody

Purpose: SFRP1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human SFRP1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SFRP1

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Alternative Name: SFRP1

Background: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling, epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009],FRP, FRP-1, FRP1, FrzA, SARP2,Apoptosis,Cell Biology & Developmental Biology,Neuroscience,Stem Cells,Ubiquitin,Wnt/β-Catenin Signaling Pathway,SFRP1

Molecular Weight: 35kDa

Gene ID: 6422

UniProt: Q8N474

Pathways: WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation