CHRNA3 antibody (N-Term)

Catalog No. ABIN2792247

The Rabbit Polyclonal anti-CHRNA3 antibody has been validated for WB. It is suitable to detect CHRNA3 in samples from Human, Mouse, Rat, Cow, Dog, Rabbit and Guinea Pig.

Quick Overview for CHRNA3 antibody (N-Term) (ABIN2792247)

Target: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHRNA3 Antibody

Binding Specificity: N-Term

Sequence: LPVARASEAE HRLFERLFED YNEIIRPVAN VSDPVIIHFE VSMSQLVKVD

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against CHRNA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 505 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRNA3

Target: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Alternative Name: CHRNA3

Background: The CHRNA3 subunit is expressed in the soma of the majority of pyramidal cells, with the most alpha 3 immunoreactivity observed in CA2-4 and entorhinal cortex and relatively less in CA1 and subicular pyramidal cell soma.
Alias Symbols: LNCR2, PAOD2, NACHRA3
Protein Interaction Partner: Ubqln1, CHRNB4,
Protein Size: 505

Molecular Weight: 57 kDa

Gene ID: 1136

NCBI Accession: NM_000743, NP_000734

UniProt: P32297

Pathways: Synaptic Membrane