TLX1 antibody (Middle Region)

Catalog No. ABIN2792533

This Rabbit Polyclonal antibody specifically detects TLX1 in WB. It exhibits reactivity toward Mouse, Human, Rat, Cow, Dog, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for TLX1 antibody (Middle Region) (ABIN2792533)

Target: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Reactivity: Mouse, Human, Rat, Cow, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TLX1 Antibody

Binding Specificity: Middle Region

Sequence: VAHPQPLATG LPTVPSVPAM PGVNNLTGLT FPWMESNRRY TKDRFTGHPY

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TLX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TLX1

Application Details

Application Notes: WB Suggested Anti-TLX1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: Human heart.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 330 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TLX1

Target: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Alternative Name: TLX1

Background: TLX1 contains 1 homeobox DNA-binding domain. TLX1 controls the genesis of the spleen. A chromosomal aberration involving TLX1, translocation t(10,14)(q24,q11) with TCRD, may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL).
Alias Symbols: HOX11, MGC163402, TCL3
Protein Interaction Partner: TLE1, PPP1CC, PPP1CB, NFIC, PPP2CA, PKNOX1, MEIS1, TLX1, PPP2CB,
Protein Size: 330

Molecular Weight: 34 kDa

Gene ID: 3195

NCBI Accession: NM_005521, NP_005512

UniProt: P31314