LYL1 antibody (N-Term)

Catalog No. ABIN2792562

The Rabbit Polyclonal anti-LYL1 antibody has been validated for WB. It is suitable to detect LYL1 in samples from Human and Pig. There is 1 publication available.

Quick Overview for LYL1 antibody (N-Term) (ABIN2792562)

Target: LYL1

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LYL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LYL1 Antibody

Binding Specificity: N-Term

Sequence: ASPGPPQVEE VGHRGGSSPP RLPPGVPVIS LGHSRPPGVA MPTTELGTLR

Cross-Reactivity: Human

Predicted Reactivity: Human: 100%, Pig: 92%

Characteristics: This is a rabbit polyclonal antibody against LYL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LYL1

Application Details

Application Notes: WB Suggested Anti-LYL1 Antibody Titration: 0.2-1 µg/mL
Positive Control: 721_B cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 280 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-LYL1 antibody (ABIN2792562)

San-Marina, Han, Suarez Saiz, Trus, Minden: "Lyl1 interacts with CREB1 and alters expression of CREB1 target genes." in: Biochimica et biophysica acta, Vol. 1783, Issue 3, pp. 503-17, (2008) (PubMed).

Target Details for LYL1

Target: LYL1

Alternative Name: LYL1

Background: LYL1 contains 1 basic helix-loop-helix (bHLH) domain. A chromosomal aberration, translocation t (7,19)(q35,p13) with TCRB, involving LYL1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL).
Alias Symbols: bHLHa18
Protein Interaction Partner: TAL1, TRIM33, DRG1, LMO1, LMO2, NFKB1, TCF3, NFKBIA, TCF4,
Protein Size: 280

Molecular Weight: 30 kDa

Gene ID: 4066

NCBI Accession: NM_005583, NP_005574

UniProt: P12980