CREB5 antibody (N-Term)

Catalog No. ABIN2792570

This Rabbit Polyclonal antibody specifically detects CREB5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit and Pig.

Quick Overview for CREB5 antibody (N-Term) (ABIN2792570)

Target: CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREB5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CREB5 Antibody

Binding Specificity: N-Term

Sequence: CSLEHEFRKA QEEESSKRNI SMHNAVGGAM TGPGTHQLSS ARLPNHDTNV

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CREB5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CREB5

Application Details

Application Notes: WB Suggested Anti-CREB5 Antibody Titration: 1.25 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 475 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CREB5

Target: CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))

Alternative Name: CREB5

Background: CREB5 belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. This protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: CRE-BPA
Protein Interaction Partner: KRTAP10-5, KRTAP10-11, KRTAP10-1, KRTAP10-9, KRTAP10-7, MGAT5B, KRT40, RIMBP3, KRTAP4-2, KRTAP9-4, KRTAP9-2, KRTAP3-2, KRTAP4-12, TSGA10, ADAMTSL4, EFEMP2, MTUS2, RBPMS, SPRY2, SPRY1, RGS20, FOSL1, TRIP6, TRAF2, MDFI, KRT15, KIFC3, FOSL2, FOS, COL8A1, TRI
Protein Size: 475

Molecular Weight: 53 kDa

Gene ID: 9586

NCBI Accession: NM_182899, NP_878902

UniProt: Q02930

Pathways: Thyroid Hormone Synthesis