CSDA antibody (C-Term)
Quick Overview for CSDA antibody (C-Term) (ABIN2792654)
Target
See all CSDA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- GPPRPRPAPA VGEAEDKENQ QATSGPNQPS VRRGYRRPYN YRRRPRPPNA
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Cross-Reactivity
- Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 91%, Pig: 100%, Rabbit: 100%, Rat: 91%
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Characteristics
- This is a rabbit polyclonal antibody against CSDA. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CSDA
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 372 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CSDA (Cold Shock Domain Protein A (CSDA))
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Alternative Name
- DNA-binding protein A
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Background
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Human DNA-binding protein (dbpA) is a member of a Y-box binding protein family containing a cold shock domain. The increased expression of Y box binding proteins in somatic cells is associated with cell proliferation and transformation.
Alias Symbols: DBPA, CSDA1, ZONAB
Protein Interaction Partner: CEP76, CEP250, UBC, SUZ12, RNF2, EZH2, BMI1, C14orf166, RTCB, NELFB, MACF1, IGF2BP3, EIF5B, MAP7, EIF2B2, EIF2B3, RFC4, PTBP1, NMT1, MRE11A, ILF2, HNRNPU, DHX9, DDX1, CSRP1, ABCF1, PARK2, SRPK3, TARDBP, ICAM1, IGSF8, HDAC11, PAN2, IL7R, IFIT3, IFIT2, ESR1
Protein Size: 372 -
Molecular Weight
- 40 kDa
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Gene ID
- 8531
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NCBI Accession
- NM_003651, NP_003642
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UniProt
- P16989
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Target
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