AARS2 antibody (N-Term)

Catalog No. ABIN2793066

This anti-AARS2 antibody is a Rabbit Polyclonal antibody detecting AARS2 in WB and IHC. Suitable for Human.

Quick Overview for AARS2 antibody (N-Term) (ABIN2793066)

Target: AARS2 (Alanyl-tRNA Synthetase 2, Mitochondrial (AARS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AARS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-AARS2 Antibody

Binding Specificity: AA 61-91, N-Term

Purpose: Rabbit Anti-Human AlaRS (AARS) (N-term) Antibody

Immunogen: This AlaRS (AARS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-91 amino acids from the N-terminal region of human AlaRS (AARS).

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of anti-AARS Pab , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for AARS2

Target: AARS2 (Alanyl-tRNA Synthetase 2, Mitochondrial (AARS2))

Alternative Name: AlaRS

Background:

Target Description: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases,of the class II enzymes.Class II tRNA synthases evolved early in evolution and are highly conserved.This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41 % identity witht the E.coli protein.tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons.They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.

Gene Symbol: AARS

Molecular Weight: 106810 Da

Gene ID: 16

UniProt: P49588