DGKA antibody (C-Term)

Catalog No. ABIN2793354

This anti-DGKA antibody is a Rabbit Polyclonal antibody detecting DGKA in WB and IHC. Suitable for Human.

Quick Overview for DGKA antibody (C-Term) (ABIN2793354)

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGKA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DGKA Antibody

Binding Specificity: AA 598-628, C-Term

Purpose: Rabbit Anti-Human DGKA (C-term) Antibody

Immunogen: This DGKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 598-628 amino acids from the C-terminal region of human DGKA.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of anti-DGKA Antibody (C-term) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for DGKA

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Alternative Name: DGKA

Background:

Target Description: Upon cell stimulation, the kinase DGKA converts the second messenger diacylglycerol into phophatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. DGKA is stimulated by calcium and phosphatidylserine, and is phosphorylated by protein kinase C. Tissue expression is in lymphocytes and oligodengroglial cells. DGKA contains 2 zinc-dependent phorbol-ester and DAG binding domains, and 2 EF-hand calcium binding domains.

Gene Symbol: DGKA

Molecular Weight: 82630 Da

Gene ID: 1606

UniProt: P23743