RGS1 antibody (N-Term)

Catalog No. ABIN2793517

This Rabbit Polyclonal antibody specifically detects RGS1 in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for RGS1 antibody (N-Term) (ABIN2793517)

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-RGS1 Antibody

Binding Specificity: AA 19-45, N-Term

Purpose: Rabbit Anti-Human RGS1 (N-term) Antibody

Immunogen: This RGS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human RGS1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50Western blot analysis of RGS1 Antibody (N-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.471 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for RGS1

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Alternative Name: RGS1

Background:

Target Description: RGS1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Gene Symbol: RGS1

Molecular Weight: 23858 Da

Gene ID: 5996

UniProt: Q08116

Pathways: MAPK Signaling, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events