Phospholamban antibody (pThr17)

Catalog No. ABIN2794308

This anti-Phospholamban antibody is a Rabbit Polyclonal antibody detecting Phospholamban in DB. Suitable for Human.

Quick Overview for Phospholamban antibody (pThr17) (ABIN2794308)

Target: Phospholamban (PLN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholamban antibody is un-conjugated

Application: Dot Blot (DB)

Product Details anti-Phospholamban Antibody

Binding Specificity: pThr17

Purpose: Rabbit Anti-Human Phospho-PLB(T17) Antibody

Immunogen: This PLB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T17 of human PLB.

Isotype: Ig Fraction

Application Details

Application Notes: Dot Blot
Recommended Dilutions
DB: 1:500
Dot blot analysis of anti-Phospho-PLB-T17 Phospho-specific Pab on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 μg per ml.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Phospholamban

Target: Phospholamban (PLN)

Alternative Name: PLB

Background:

Target Description: Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases, whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.

Gene Symbol: PLN

Molecular Weight: 6109 Da

Gene ID: 5350

UniProt: P26678

Pathways: Negative Regulation of Transporter Activity