CLCN1 antibody (AA 2459-2488)

Catalog No. ABIN2794858

This Rabbit Polyclonal antibody specifically detects CLCN1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for CLCN1 antibody (AA 2459-2488) (ABIN2794858)

Target: CLCN1 (Chloride Channel 1, Skeletal Muscle (CLCN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CLCN1 Antibody

Binding Specificity: AA 2459-2488

Purpose: Rabbit Anti-Human mTOR (FRAP1) (S2481) Antibody

Immunogen: This mTOR (FRAP1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2459-2488 amino acids from human mTOR (FRAP1).

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, IF: 1:10-50Western blot analysis of FRAP1 (arrow) using rabbit polyclonal FRAP1 Antibody (S2481) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.350 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for CLCN1

Target: CLCN1 (Chloride Channel 1, Skeletal Muscle (CLCN1))

Alternative Name: mTO

Background:

Target Description: FRAP1 belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. FRAP1 is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.

Gene Symbol: MTOR

Molecular Weight: 288892 Da

Gene ID: 2475

UniProt: P42345