CLCN1 antibody (C-Term)

Catalog No. ABIN2776080

The Rabbit Polyclonal anti-CLCN1 antibody is suitable to detect CLCN1 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Goat and Rabbit. It has been validated for WB.

Quick Overview for CLCN1 antibody (C-Term) (ABIN2776080)

Target: CLCN1 (Chloride Channel 1, Skeletal Muscle (CLCN1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Goat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLCN1 Antibody

Binding Specificity: C-Term

Purpose: Clcn1 Antibody - C-terminal region

Sequence: SSIFQRLLHC LLGKAHSTKK KITQDSTDLV DNMSPEEIEA WEREQLSQPV

Predicted Reactivity: Cow: 93%, Dog: 86%, Goat: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Clcn1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34912-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CLCN1

Target: CLCN1 (Chloride Channel 1, Skeletal Muscle (CLCN1))

Alternative Name: Clcn1

Background:

Background Information: Clcn1 is the voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport.

Gene Name: Chloride channel 1, skeletal muscle

Alternative Symbols: SMCC

Protein Name: Chloride channel protein 1

Molecular Weight: 110kDa

Gene ID: 25688

NCBI Accession: NP_037279

UniProt: P35524