Glucagon antibody (C-Term)

Catalog No. ABIN2795036

The Rabbit Polyclonal anti-Glucagon antibody has been validated for WB, IHC, IF, FACS and Agon. It is suitable to detect Glucagon in samples from Human.

Quick Overview for Glucagon antibody (C-Term) (ABIN2795036)

Target: Glucagon (GCG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucagon antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Agonist (Agon)

Product Details anti-Glucagon Antibody

Binding Specificity: AA 119-148, C-Term

Purpose: Rabbit Anti-Human Glucagon (C-term) Antibody

Immunogen: This Glucagon antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the C-terminal region of human Glucagon.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, IF: 1:10-50, FC: 1:10-50Western blot analysis of Glucagon Antibody (C-term) . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Glucagon

Target: Glucagon (GCG)

Alternative Name: Glucagon

Background:

Target Description: Glucagon is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Gene Symbol: GCG

Molecular Weight: 20909 Da

Gene ID: 2641

UniProt: P01275

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling