Aurora Kinase C antibody (N-Term)

Catalog No. ABIN2795119

This Rabbit Polyclonal antibody specifically detects Aurora Kinase C in WB and IF. It exhibits reactivity toward Human.

Quick Overview for Aurora Kinase C antibody (N-Term) (ABIN2795119)

Target: Aurora Kinase C (AURKC)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aurora Kinase C antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Aurora Kinase C Antibody

Binding Specificity: AA 3-38, N-Term

Purpose: Rabbit Anti-Human Aurora-C (N-term) Antibody

Immunogen: This Aurora-C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-38 amino acids from the N-terminal region of human Aurora-C.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000The anti-Aurora C Pab .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Aurora Kinase C

Target: Aurora Kinase C (AURKC)

Alternative Name: Aurora-C

Background:

Target Description: Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

Gene Symbol: AURKC

Molecular Weight: 35591 Da

Gene ID: 6795

UniProt: Q9UQB9

Pathways: Cell Division Cycle, Maintenance of Protein Location