FZD7 antibody (Center)

Catalog No. ABIN2795184

This anti-FZD7 antibody is a Rabbit Polyclonal antibody detecting FZD7 in WB. Suitable for Human.

Quick Overview for FZD7 antibody (Center) (ABIN2795184)

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FZD7 Antibody

Binding Specificity: AA 202-229, Center

Purpose: Rabbit Anti-Human FZD7 (Center) Antibody

Immunogen: This FZD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human FZD7.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000FZD7 Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for FZD7

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Alternative Name: FZD7

Background:

Target Description: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Gene Symbol: FZD7

Molecular Weight: 63620 Da

Gene ID: 8324

UniProt: O75084

Pathways: WNT Signaling, Stem Cell Maintenance